J. Travis Hinson, MD
J. Travis Hinson, MD, utilizes genomic approaches like CRISPR/Cas to interrogate mechanisms of inherited cardiovascular disorders, especially those that lead to heart failure. He is particularly interested in developing single-cell and cardiac-microtissue assays derived from disease-specific, human induced pluripotent stem cells in combination with in vivo mouse models. His lab’s current research focus is:
- To define the role of AMP-activated protein kinase in physiologic and pathologic forms of cardiac remodeling
- To engineer cardiac microtissues to study the most common forms of familial hypertrophic and dilated cardiomyopathies due to sarcomere mutations
- To develop assays for high-throughput functional genomic screens to predict pathogenicity of genetic variation in cardiomyopathy genes
These studies capitalize on the lab’s expertise in human genetics, stem cell biology, tissue engineering, and computational methods.
While the Hinson Lab is at the Jackson Laboratory, he also maintains a clinical practice treating patients with inherited cardiovascular diseases at the University of Connecticut Cardiology division.
Hosted by Benoit Bruneau, PhD
The GICD/CVRI Seminar series is a collaborative series between the Gladstone Institute of Cardiovascular Disease and the Cardiovascular Research Institute at UC San Francisco.
Diversity, Equity, and Inclusion
At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.
We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.