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Researchers trained a computer model to understand the connections between thousands of genes—and pinpoint how those connections go awry in human disease
News Release Research (Publication) Cardiovascular Disease Theodoris Lab
High levels of oxygen can cause lasting health problems in humans. Now scientists know why.
News Release Research (Publication) Cardiovascular Disease Jain Lab CRISPR/Gene Editing
When mice are exposed to chronically low levels of oxygen, similar to those experienced at 4,500 meters of elevation, their metabolism changes
News Release Research (Publication) Cardiovascular Disease Jain Lab
A Q&A with Gladstone Investigator Benoit Bruneau
Research (Publication) Congenital Heart Disease Cardiovascular Disease Bruneau Lab
Revisit some of Gladstone’s most important stories from the past year
Gladstone Experts Cardiovascular Disease Data Science and Biotechnology Genomic Immunology Neurological Disease Virology
Gladstone researchers talk about the power of iPS cells in biomedical research
Stem Cells/iPSCs Cardiovascular Disease Stem Cell Core
Christina Theodoris joins Gladstone as an assistant investigator to find new therapies for people with life-threatening cardiovascular diseases
Institutional News News Release Profile Cardiovascular Disease Data Science and Biotechnology Theodoris Lab
Michael Alexanian joins Gladstone Institutes to discover new targets for treating and reversing heart failure
Institutional News News Release Profile Heart Failure Cardiovascular Disease Alexanian Lab
Catherine Tcheandjieu joins Gladstone Institutes to uncover what predisposes people from diverse ancestries to disease
Institutional News News Release Profile Cardiovascular Disease Data Science and Biotechnology Tcheandjieu Lab
The APQC Blog—Gladstone President Deepak Srivastava, MD, President Emeritus Robert Mahley, MD, PhD, Senior Investigators Melanie Ott, MD, PhD, and Katie Pollard, PhD, explain how they and others at Gladstone create a collaborative research culture and plan to balance safety with the chance encounters that fuel creativity.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Huang Lab Ott Lab Pollard Lab Srivastava Lab Weinberger Lab
San Jose Mercury News—Senior Investigators Melanie Ott, MD, PhD, and Bruce Conklin, MD, recount how they used miniature balls of beating heart cells called organoids to study the effects of COVID-19 on the heart. The heart cells were derived from a person's skin cells, thanks to technology pioneered by Senior Investigator and Nobel Laureate Shinya Yamanaka, MD, PhD.
Gladstone Experts Stem Cell Core COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Conklin Lab Ott Lab Yamanaka Lab Organoids
Gladstone researchers develop robust strategy for sifting through large-scale genetic data to better understand congenital heart problems
News Release Research (Publication) Congenital Heart Disease Cardiovascular Disease Krogan Lab Pollard Lab Srivastava Lab Stem Cells/iPSCs
Removing one gene from developing heart cells suddenly makes them turn into brain cell precursors, making researchers rethink cellular identity
News Release Research (Publication) Cardiovascular Disease Bruneau Lab Stem Cells/iPSCs Hota
Gladstone scientists create novel organoids that open new doors for understanding crosstalk between tissues during human development
News Release Research (Publication) Cardiovascular Disease McDevitt Lab Organoids
Scientific American—There is increasing evidence that some people who recover from COVID-19 suffer from lingering heart problems, a phenomenon known as post-COVID-19 cardiac syndrome. Senior Investigator Bruce Conklin explains that it’s important to investigate the long-term consequences of infection, and describes his team’s work showing that infecting heart cells with SARS-CoV-2 can result in dramatic structural damage.
Gladstone Experts COVID-19 Cardiovascular Disease Conklin Lab
