Gladstone scientists have discovered how the apoE4 gene—the primary genetic risk factor for Alzheimer’s disease—disrupts the brain’s network activity and impairs memory. 

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Drs. Huang, Ding, Srivastava

In a major breakthrough, Gladstone scientists transformed skin cells into heart cells and brain cells using a combination of chemicals and without adding external genes to the cells.

Drs. Bruce Conklin and Nathaniel Huebsch

Gladstone scientists have invented a new way to create micro heart muscle from stem cells using a unique dog bone dish. The three-dimensional tissue is ideal for disease modeling and drug testing.

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