Gladstone-UCSF Institute of Genomic Immunology Seminar
Tuesday, March 12, 2024

Stephen Elledge, PhD

Gregor Mendel Professor of Genetics and Medicine at the Department of Genetics of Harvard Medical School and in the Division of Genetics of the Brigham and Women’s Hospital

Stephen Elledge, PhD, is the Gregor Mendel Professor of Genetics and Medicine at Harvard Medical School. He is also an Investigator of the Howard Hughes Medical Institute. Dr. Elledge is best known for elucidating how eukaryotic cells sense and respond to DNA damage. He has identified key DNA damage response genes both in yeast and mammalian cells, showed how the damage-response pathway is activated by DNA lesions, and made key contributions to defining the cascade of events that enforces cell cycle arrest and controls DNA repair. Elledge's work is marked by the development of powerful research tools to uncover the network of genes involved in sensing and repairing DNA damage. His pioneering work laid the foundation for our current understanding of how failures in DNA damage sensing relate to the medically important field of genome instability. His lab is also focused on generating new genetic technologies, including recent advances in the high-throughput determination of E3 ligase substrates and identification of T cell epitopes. 

Working on a variety of projects in diverse areas of study, Elledge and his team are elucidating critical mechanisms in cell division, cell aging, cancer growth, and protein breakdown and recycling, while also developing genetic technologies to advance discovery in areas such as autoimmune disease, viral function, and vaccine design.

Details

Dates
March 12, 2024
Time
10:00-11:00am PDT
Location
Gladstone Mahley Auditorium & Online
Audience
Gladstone and UCSF
Contact(s)







The Gladstone-UCSF Institute of Genomic Immunology Seminar Series showcases speakers at the intersection of genomic technology and immunology research with an aim to engineer the human immune system for therapeutic benefit. Speakers span technology development, synthetic biology, bioengineering, and the development and clinical application of immunotherapy. These talks are open to the Gladstone and UCSF communities.

Diversity, Equity, and Inclusion

At Gladstone, we are committed to providing events and professional development activities that resonate with our community’s diverse members. Our goal is to develop creative programming that encompasses a wide variety of ideas and perspectives to inspire, educate, and engage with everyone within our walls.

We want to effect positive change through our events and activities by providing a platform for discussions on important topics related to increasing diversity and inclusiveness in the sciences.