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Publications

  1. Singh SV, Srivastava D, Haque AK, Awasthi YC. (1985) Glutathione S-transferases of human heart. IRCS Med. Sci. 13:973–974.
  2. Thompson EB, Srivastava D, Johnson BH. (1989) Interactions of the phenylpyrazolo steroid cortivazol with glucocorticoid receptors in steroid-sensitive and -resistant human leukemic cells. Cancer Res. 49:2253s–2258s.
  3. Srivastava D, Thompson EB. (1990) Two glucocorticoid binding sites on the human glucocorticoid receptor. Endocrinology. 127:1770–1778.
  4. Srivastava D, Cserjesi P, Olson EN. (1995) A subclass of bHLH proteins required for cardiac morphogenesis. Science 270:1995–1999.
  5. Srivastava D, Preminger T, Lock JE, Mandell V, Keane JF, Mayer JE, Jr., Kozakewich H, Spevak PJ. (1995) Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Circulation 92:1217–1222.
  6. Srivastava D, Olson EN. (1996) Neurotrophin-3 knocks heart off Trk. Nat. Med. 2:1069–1071. [PDF - 420 KB]
  7. Olson EN, Srivastava D. (1996) Molecular pathways controlling heart development. Science 272:671–676.
  8. Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN. (1997) Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND. Nat. Genet. 16:154–160. [PDF - 933 KB]
  9. Srivastava D. (1997) Left, right ... which way to turn? Nat. Genet. 17:252–254. [PDF - 413 KB]
  10. Lin Q, Srivastava D, Olson EN. (1997) A transcriptional pathway for cardiac development. Cold Spring Harb. Symp. Quant. Biol. 62:405–411.
  11. Srivastava D. (1997) The bHLH proteins, dHAND and eHAND in cardiac development. In: Harvey RP, Olson EN, Schulz RA, Altman JS, eds. Genetic Control of Heart Development Strasbourg: HFSP.
  12. Srivastava D, Olson EN. (1997) Knowing in your heart what's right. Trends Cell Biol. 7:447–453. [PDF - 766 KB]
  13. Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D. (1998) The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Dev. Biol. 196:228–236. [PDF - 3.06 MB]
  14. Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, Olson EN, Srivastava D. (1998) A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme. Development 125:3005–3014. [PDF - 503 KB]
  15. Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN. (1998) Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat. Genet. 18:266–270. [PDF - 821 KB]
  16. Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. (1999) HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev. Biol. 216:72–84. [PDF - 1.15 MB]
  17. Srivastava D, Yamagishi H. (1999) Role of the dHAND-UFD1L pathway. Trends Genet. 15:253–254. [PDF - 120 KB]
  18. Srivastava D. (1999) Developmental and genetic aspects of congenital heart disease. Curr. Opin. Cardiol. 14: 263–268.
  19. Srivastava D. (1999) HAND proteins: Molecular mediators of cardiac development and congenital heart disease. Trends Cardiovasc. Med. 9:11–18. [PDF - 418 KB]
  20. Yamagishi H, Garg V, Matsuoka R, Thomas T, Srivastava D. (1999) A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects. Science 283:1158–1161. [PDF - 792 KB]
  21. Srivastava D (1999) Segmental regulation of cardiac development by the basic helix-loop-helix transcription factors dHAND and eHAND. In Heart Development (Rosenthal N, Harvey R, eds.) 1st Ed., pp. 143–155, Academic Press.
  22. Kathiriya IS, Srivastava D. (2000) Left-right asymmetry and cardiac looping: Implications for cardiac development and congenital heart disease. Am. J. Med. Genet. 97: 271–279. [PDF - 314 KB]
  23. Nakagawa O, McFadden DG, Nakagawa M, Yanagisawa H, Hu T, Srivastava D, Olson EN. (2000) Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proc. Natl. Acad. Sci. USA 97:13655–13660. [PDF - 301 KB]
  24. McFadden DG, Charite J, Richardson JA, Srivastava D, Firulli AB, Olson EN. (2000) A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart. Development 127:5331–5341. [PDF - 558 KB]
  25. Fisher SA, Langille BL, Srivastava D. (2000) Apoptosis during cardiovascular development. Circ. Res. 87: 856–864. [PDF - 687 KB]
  26. Srivastava D, Olson EN. (2000) A genetic blueprint for cardiac development. Nature 407:221–226. [PDF - 308 KB]
  27. Srivastava D. (2000) Congenital heart defects: Trapping the genetic culprits. Circ. Res. 86:917–918. [PDF - 31 KB]
  28. Angelo S, Lohr J, Lee KH, Ticho BS, Breitbart RE, Hill S, Yost HJ, Srivastava D. (2000) Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development. Mech. Dev. 95:231–237. [PDF - 5.97 MB]
  29. Fernandez-Teran M, Piedra ME, Kathiriya IS, Srivastava D, Rodriguez-Rey JC, Ros MA. (2000) Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway. Development 127:2133–2142. [PDF - 340 KB]
  30. Yamagishi H, Olson EN, Srivastava D. (2000) The bHLH transcription factor, dHAND, is required for vascular development. J. Clin. Invest. 105:261–270. [PDF - 3.38 MB]
  31. Srivastava D. (2000) DiGeorge syndrome: An enigma in mice and men. Mol. Med. Today 6:13–14. [PDF - 35 KB]
  32. Srivastava D (2000) Understanding CHD through dissection of segmental cardiac molecular pathways. In Etiology and Morphogenesis of Congenital Heart Disease (Takao A, Nakazawa M, Clark EB, eds.) pp. 205–210, Futura, Armonk, NY.
  33. Yamagishi H, Srivastava D (2000) Role of the bHLH transcription factor, dHAND, in cranial/cardiac neural crest development. In Etiology and Morphogenesis of Congenital Heart Disease: Twenty Years of Progress in Genetics and Developmental Biology (Clark EB, Nakazawa M, Takao A, eds.) pp. 325–328, Futura, Armonk, NY.
  34. Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D. (2001) The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation. Dev. Biol. 239:190–203. [PDF - 5.54 MB]
  35. Kunte A, Ivey K, Yamagishi C, Garg V, Yamagishi H, Srivastava D. (2001) A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L. Mech. Dev. 108:81–92. [PDF - 948 KB]
  36. Natarajan A, Yamagishi H, Ahmad F, Li D, Roberts R, Matsuoka R, Hill S, Srivastava D. (2001) Human eHAND, but not dHAND, is down-regulated in cardiomyopathies. J. Mol. Cell. Cardiol. 33:1607–1614. [PDF - 202 KB]
  37. Garg V, Yamagishi C, Hu T, Kathiriya IS, Yamagishi H, Srivastava D. (2001) Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development. Dev. Biol. 235:62–73.
  38. Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN. (2001) CHAMP, a novel cardiac-specific helicase regulated by MEF2C. Dev. Biol. 234:497–509. [PDF - 491 KB]
  39. Srivastava D. (2001) Genetic assembly of the heart: Implications for congenital heart disease. Annu. Rev. Physiol. 63:451–469. [PDF - 376 KB]
  40. Srivastava D, Baldwin HS (2001) Molecular determinants of cardiac development. In Moss and Adams' Heart Disease in Infants, Children, and Adolescents (Allen HD, Gutsgell HP, Clark EB, Driscoll DJ, eds.) 6th Ed., pp. Lippincott Williams & Wilkins, Baltimore.
  41. Olson EN, Srivastava D (2001) HAND transcription factors. In Encyclopedia of Molecular Medicine (Creighton TE, Kazazian HH, eds.) John Wiley & Sons.
  42. Srivastava D, Gottlieb PD, Olson EN. (2002) Molecular mechanisms of ventricular hypoplasia. Cold Spring Harb. Symp. Quant. Biol. 67:121–125.
  43. Villanueva MP, Aiyer AR, Muller S, Pletcher MT, Liu X, Emanuel B, Srivastava D, Reeves RH. (2002) Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene. Genomics 80:593–600. [PDF - 117 KB]
  44. Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K. (2002) Tooth-type specific expression of dHAND/Hand2: Possible involvement in murine lower incisor morphogenesis. Cell Tissue Res. 310:201–212. [PDF - 891 KB]
  45. Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D. (2002) Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat. Genet. 31:25–32. [PDF - 1.19 MB]
  46. Srivastava D (2002) Molecular and morphogenetic cardiac embryology: Implications for congenital heart disease. In Neonatal Cardiology (Artman M, Mahony L, Teitel DF, eds.) pp. 1–15, McGraw-Hill.
  47. Yamagishi H, Srivastava D. (2003) Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome. Trends Mol. Med. 9:383–389. [PDF - 850 KB]
  48. Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D. (2003) GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature 424:443–447. [PDF - 394 KB]
  49. Srivastava D. (2003) Building a heart: Implications for congenital heart disease. J. Nucl. Cardiol. 10:63–70. [PDF - 301 KB]
  50. Yamagishi C, Hierck BP, Gittenberger-De Groot AC, Yamagishi H, Srivastava D. (2003) Functional attenuation of UFD1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos. Pediatr. Res. 53:546–553. [PDF - 3.17 MB]
  51. Ivey K, Tyson B, Ukidwe P, McFadden DG, Levi G, Olson EN, Srivastava D, Wilkie TM. (2003) Gaq and Ga11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme. Dev. Biol. 255: 230–237. [PDF - 819 KB]
  52. Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D. (2003) Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 17:269–281. [PDF - 919 KB]
  53. Srivastava D (2003) Signaling Pathways Involved in Cardiogenesis. In Handbook of Cell Signaling (Bradshaw RA, Dennis EA, eds.) Vol. 3, pp. 463–470, Academic Press.
  54. Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. (2004) Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature 432:466–472. [PDF - 451 KB]
  55. Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O. (2004) Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism. J. Biol. Chem. 279:54937–54943. [PDF - 312 KB]
  56. Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M. (2004) Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev. Biol. 271:263–271. [PDF - 955 KB]
  57. Srivastava D. (2004) Heart disease: An ongoing genetic battle? Nature 429:819–822. [PDF - 935 KB]
  58. Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D. (2004) Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development 131:5491–5502. [PDF - 1 MB]
  59. Srivastava D, Olson EN (2004) Cardiac Development and Congenital Heart Disease. In Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease (Chien KR, eds.) 2nd Ed., pp. W.B. Saunders, Philadelphia.
  60. Aiyer AR, Honarpour N, Herz J, Srivastava D. (2005) Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype. Dev. Biol. 278:155–162. [PDF - 631 KB]
  61. McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN. (2005) The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development 132:189–201.
  62. Garg V, Srivastava D (2005) Genetic underpinnings of cardiogenesis and congenital heart disease. In Principles of Molecular Cardiology (Runge MS, Patterson C, eds.) pp. Humana Press, Totowa, NJ.
  63. Zhao Y, Samal E, Srivastava D. (2005) Serum response factor regulates a muscle-specific mircroRNA that targets Hand2 during cardiogenesis. Nature 436:214-220. [PDF - 572 KB]
  64. Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D. (2005) Mutations in NOTCH1 cause aortic valve disease. Nature 437:270–274. [PDF - 425 KB]
  65. Costantini DL, Arruda EP, Agarwal P, Kim K-H, Zhu Y, Lebel M, Cheng CW, Park CY, Pierce S, Guerchicoff A, Pollevick G, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui C-C, Backx PH, Bruneau BG. (2005) The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 123:347–358.
  66. Kwon C, Han Z, Olson EN, Srivastava D. (2005) MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Natl. Acad. Sci. USA 102:18986–18991. [PDF - 1.1 MB].
  67. Srivastava D. (2006) Genetic regulation of cardiogenesis and congenital heart disease. Ann. Rev. Pathol.: Mech. Dis. 1:199–213. [PDF - 280 KB]
  68. Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG. (2006) Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat. Genet. 38: 175–183.
  69. Maeda J, Yamagishi H, McAnally J, Yamagishi C, Srivastava D. (2006) Tbx1 is regulated by forkhead proteins in the secondary heart field. Dev. Dyn. 235:701–710. [PDF - 540 KB].
  70. Yamagishi C, Yamagishi H, Maeda J, Tsuchihashi T, Ivey K, Hu T, Srivastava D. (2006) Sonic hedgehog is essential for first pharyngeal arch development. Pediatr. Res. 59:349–354.
  71. King IN, Kathiriya IS, Murakami M, Nakagawa M, Gardner KA, Srivastava D, Nakagawa O. (2006) Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa. Biochem. Biophys. Res. Commun. 345:446–452. [PDF - 372 KB]
  72. Srivastava D, Ivey KN. (2006) Potential of stem cell-based therapies for heart disease. Nature 441:1097–1099. [PDF - 345 KB]
  73. Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L. (2006) Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development 133:2263–2273. [PDF - 6.5 MB]
  74. Srivastava D, Yu S. (2006) Stretching to meet needs: Integrin-linked kinase and the cardiac pump. Genes Dev. 20:2327–2331. [PDF - 212 KB]
  75. Gong B, Trent MB, Srivastava D, Boor PJ. (2006) Chemical-induced, nonlethal, developmental model of dissecting aortic aneurysm. Birth Defects Res. A Clin. Mol. Teratol. 76:29–38. [PDF - 894 KB]
  76. Ivey K, Srivastava D. (2006) The paradoxical patent ductus arteriosus. J. Clin. Invest. 116:2863–2865 . [PDF - 353 KB]
  77. Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK. (2006) Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation 114:1838–1846. [PDF - 1 MB]
  78. Srivastava D. (2006) Making or breaking the heart: From lineage determination to morphogenesis. Cell 126:1037–1048 [PDF - 715 KB]
  79. Ransom J, Srivastava D. (2007) The genetics of cardiac birth defects. Semin. Cell Dev. Biol. 18:132–139.
  80. Zhao Y, Srivastava D. (2007) A developmental view of microRNA function. Trends Biochem. Sci. 32:189–197. [PDF -634 KB]
  81. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. (2007) Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129:303–317. [PDF - 2 MB]
  82. Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. (2007) Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc. Natl. Acad. Sci. USA 104:7975–7980. [PDF - 1.34 MB]
  83. Pierpont ME, Basson CT, Benson DW, Jr., Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL. (2007) Genetic basis for congenital heart defects: Current knowledge: A scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation 115:3015–3038. [PDF - 327 KB]
  84. Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D. (2007) Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc. Natl. Acad. Sci. USA 104:10894–10899. [PDF - 928 KB]
  85. Samal E, Srivastava D. (2007) Role of microRNAs in Cardiovascular Biology. In Advances in Developmental Biology (Bodmer R, eds) Vol 18, Elsevier, pp 167–178.
  86. Schluterman MK, Krysiak AE, Kathiriya IS, Abate N, Chandalia M, Srivastava D, Garg V. (2007) Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease. Am. J. Med. Genet. A 143:817–823. [PDF - 1 MB]
  87. Jia H, King IN, Chopra SS, Wan H, Ni TT, Jiang C, Guan X, Wells S, Srivastava D, Zhong TP. (2007) Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5. Proc. Natl. Acad. Sci. USA 104:14008–14013.
  88. Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Woodrow Benson D, Smoot LB, Pu WT. (2007) Spectrum of heart disease associated with murine and human GATA4 mutation. J. Mol. Cell. Cardiol. 43:677–685. [PDF - 1.77 MB]
  89. Srivastava D, Saxena A, Dimaio JM, Bock-Marquette I. (2007) Thymosin beta 4 is cardioprotective after myocardial infarction. Ann. NY Acad. Sci. 1112:161–170. [PDF - 185 KB]
  90. Ivey KN, Muth A, Arnold J, King FW, Yeh R-F, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. (2008) MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2:219–229. [PDF - 1.6 MB]
  91. Saxena A, Fish JE, White MD, Yu S, Smyth JWP, Shaw RM, DiMaio JM, Srivastava D. (2008) Stromal cell-derived factor-1 alpha is cardioprotective after myocardial infarction. Circulation 117:2224–2231. [PDF - 580 KB]
  92. Nigam V, Srivastava D. (2008) Molecular regulation of cardiogenesis. In Inborn Errors of Development (Epstein CJ, eds) 2nd Edition, Oxford University, Oxford, pp 124–129.
  93. Ivey KN, Sutcliffe D, Richardson J, Clyman RI, Garcia JA, Srivastava D. (2008) Transcriptional regulation during development of the ductus arteriosus. Circ. Res. 103:388–395. [PDF - 1.27 MB]
  94. Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DYR, Srivastava D. (2008) miR-126 regulates angiogenic signaling and vascular integrity. Dev. Cell 15:272–284. [PDF - 1.79 MB]
  95. Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DYR, Srivastava D. (2008) microRNA-138 modulates cardiac patterning during embryonic development. Proc. Natl. Acad. Sci. USA 105:17830–17835. [PDF - 722 KB]
  96. Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ. (2008) Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc. Natl. Acad. Sci. USA 105:17824–17829. [PDF - 1.92 MB]
  97. Ransom JF, King IN, Garg V, Srivastava D. (2008) A rare human sequence variant reveals myocardin autoinhibition. J. Biol. Chem. 283:35845–35852. [PDF - 610 KB]
  98. Kwon C, Cordes KR, Srivastava D. (2008) Wnt/β-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. Cell Cycle 7:3815–3818.
  99. Fish JE, Srivastava D. (2009) microRNAs: Opening a new vein in angiogenesis research. Sci. Signal. 2:pe1. [PDF - 218 KB]
  100. Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V. (2009) Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev. Biol. 326:368–377.
  101. Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong T-T, Shaw RM, Srivastava D. (2009) Cardiac fibroblasts regulate myocardial proliferation through beta-1 integrin signaling. Dev. Cell 16:233–244. [PDF - 2.26 MB]
  102. Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. (2009) Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell 4:198–199; author reply 202. [PDF - 83 KB]
  103. Cordes KR, Srivastava D. (2009) MicroRNA regulation of cardiovascular development. Circ. Res. 104:724–732. [PDF - 560 KB]
  104. Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN, DiMaio JM. (2009) Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J. Mol. Cell. Cardiol. 46:728–738.
  105. Cordes KR, Sheehy NT, White M, Berry E, Morton SU, Muth AN, Lee T-H, Miano JM, Ivey KN, Srivastava D. (2009) miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (article) 460:705–710. [PDF - 816 KB]
  106. Shieh JT, Srivastava D. (2009) Heart malformation: What are the chances it could happen again? Circulation 120:269-71. [PDF - 307 KB]
  107. Kwon C, Qian L, Cheng P, Nigam V, Arnold J, Srivastava D. (2009) A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. Nat. Cell Biol. 11:951–957. [PDF - 1.19 MB]
  108. Nigam V, Srivastava D. (2009) Notch1 represses osteogenic pathways in aortic valve cells. J. Mol. Cell. Cardiol. 47:828–834. [PDF - 690 KB]
  109. Srivastava D, Kwon C. (2009) Signaling pathways involved in cardiogenesis. In Handbook of Cell Signaling (Bradshaw RA, Dennis EA, eds) 2nd Edition, Vol. 3, Academic Press, Oxford, pp 2601–2609.
  110. Bruneau BG, Burn J, Srivastava D. (2010) The Aetiology of Congenital Cardiac Disease. In Paediatric Cardiology (Anderson RH, Baker EJ, Penny D, Redington AN, Rigby ML, Wernovsky G, eds) 3rd Edition, Churchill Livingstone, Philadelphia, pp 161–171.
  111. Fish JE, Yan MS, Matouk CC, St. Bernard R, Ho JD, Jr., Gavryushova A, Srivastava D, Marsden PA. (2010) Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J. Biol. Chem. 285:810–826.
  112. Cordes KR, Srivastava D. (2010) MicroRNA regulation of cardiac development and disease. In: Rosenthal N, Harvey R, eds. Heart Development and Regeneration. San Diego: Academic Press, Elsevier; 729–740.
  113. Cordes KR, Srivastava D, Ivey KN. (2010) MicroRNAs in cardiac development. Pediatr. Cardiol. 31:349–356. [PDF - 454 KB]
  114. Qian L, Srivastava D. (2010) Monkeying around with cardiac progenitors: Hope for the future. J. Clin. Invest. 120:1034–1036. [PDF - 396 KB]
  115. van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D. (2010) Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ. Res. 107:304–347. [PDF - 1.2 MB]
  116. Ivey KN, Srivastava D. (2010) MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell. 7:36–41. [PDF - 332 KB]
  117. Ieda M, Fu J, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. (2010) Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142:375–386. [PDF - 1.94 MB]
  118. Nigam V, Sievers HH, Jensen BC, Sier HA, Simpson PC, Srivastava D and Mohamed SA. (2010) Altered microRNAs in bicuspid aortic valve: A comparison between stenotic and insufficient valves. J. Heart Valve Dis. 19:459–465. [PDF - 197 KB]
  119. Maitra M, Koenig SN, Srivastava D and Garg V. (2010) Identification of GATA6 sequence variants in patients with congenital heart defects. Ped. Res. 68:281–285.
  120. Sheehy NT, Cordes KR, White MP, Ivey KN and Srivastava D. (2010) The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch. Development 137:4307–4316. [PDF - 1.79 MB]
  121. Shrivastava S, Srivastava D, Olson EN, DiMaio JM and Bock-Marquette I. (2010) Thymosin beta4 and cardiac repair. Ann. NY Acad. Sci. 1194:87–96. [PDF - 1.29 MB]
  122. Park CY, Pierce SA, von Drehle M, Ivey KN, Morgan J, Blau HM and Srivastava D. (2010) skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. Proc. Natl. Acad. Sci. USA 107:20750–20755. [PDF - 1.35 MB]
  123. Srivastava D. Control of Embryologic Cardiac Development. In Rudolph's Pediatrics (Rudolph C, Rudolph A, Lister G, First L, Gershon A, eds) 22nd Edition, McGraw-Hill, New York.
  124. Alrais F, Feldstein VA, Srivastava D, Gosnell K and Moon-Grady AJ. (2011) Monochorionic twins discordant for congenital heart disease: A referral center's experience and possible pathophysiologic mechanisms. Prenat. Diagn. 31:978–984.
  125. Yu S, Crawford D, Tsuchihashi T, Behrens TW and Srivastava D. (2011) The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev. Dyn. 240:384–393. [PDF - 5.74 MB]
  126. Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H and Srivastava D. (2011) Hand2 function in second heart field progenitors is essential for cardiogenesis. Dev. Biol. 351:62-69. [PDF - 1.58 MB]
  127. Li Q, Kannan A, Demayo FJ, Lydon JP, Cooke PS, Yamagishi H, Srivastava D, Bagchi MK and Bagchi IC. (2011) The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science 331:912–916. [PDF - 7.3 MB]
  128. Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DYR, Srivastava D and Woo S. (2011) A novel Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. Development 138:1409–1419. [PDF - 2.91 MB]
  129. Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF and Srivastava D. (2011) miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J. Exp. Med. 208:549–560. [PDF - 2.91 MB]
  130. King IN, Qian L, Liang J, Huang Y, Shieh JTC, Kwon C, Srivastava D. (2011) A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev. Cell 20:497–510. [PDF - 1.85 MB]
  131. Shieh JTC, Huang Y, Gilmore J, Srivastava D. (2011) Elevated miR-499 levels blunt the cardiac stress response. PLoS ONE 5:e19481.[PDF - 962 KB]
  132. Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, . . . Bodmer R. (2011) Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J. Cell Biol. 193:1181–1196. [PDF - 3.9 MB]
  133. Roach JC, Glusman G, Hubley R, Montsaroff SZ, Holloway AK, Mauldin DE, . . . Smit AF. (2011) Chromosomal haplotypes by genetic phasing of human families. Am. J. Hum. Genet. 89:382–397.
  134. Kwon C, Cheng P, King IN, Andersen P, Shenje L, Nigam V, Srivastava D. (2011) Notch post-translationally regulates beta-catenin protein in stem and progenitor cells. Nat. Cell Biol. 13:1244–1251. [PDF - 1.6 MB]
  135. Bernstein HS and Srivastava D. (2012) Stem cell therapy for cardiac disease. Pediatr. Res. 71:491–499. [PDF - 221 KB]
  136. Funato N, Nakamura M, Richardson JA, Srivastava D and Yanagisawa H. (2012) Tbx1 regulates oral epithelial adhesion and palatal development. Hum. Mol. Genet. 21:2524–2537.
  137. Kathiresan S and Srivastava D. (2012) Genetics of human cardiovascular disease. Cell 148:1242–1257. [PDF - 795 KB]
  138. Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu J and Srivastava D. (2012) In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 485:593–598. [PDF - 1.4 MB]
  139. Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y,         Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, de Jong PJ, Bluestone JA, Srivastava D, McManus MT. (2012) A resource for the conditional ablation of microRNAs in the mouse. Cell Reports 1:385–391. [PDF - 831 KB]
  140. Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V. (2012) Congenital heart disease–causing Gata4 mutation displays functional deficits in vivo. PLoS Genet. 8:e1002690. [PDF - 4.7 MB]
  141. Srivastava D and Ieda M. (2012) Critical factors for cardiac reprogramming. Circ. Res. 111:5–8. [PDF - 225 KB]
  142. Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S. (2012) Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell 11:91–99. [PDF - 769 KB]
  143. Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DYR, Srivastava D. (2012) miR-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting VEGF signaling. Circ. Res. 111:1421–1433. [PDF - 1.8 MB]
  144. Baldwin HS, Srivastava D. (2012) Molecular Determinants of Cardiac Development and Disease. In Moss and Adams' Heart Disease in Infants, Children and Adolecsents (Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, eds) 8th Edition, Lippincott Williams & Wilkins, Philadelphia.
  145. Srivastava D, Ieda M, Fu J, Qian L. (2012) Cardiac repair with thymosin beta4 and cardiac reprogramming factors. Ann. NY Acad. Sci. 1270:66–72. [PDF - 945 KB]
  146. Vedantham V, Evangelista M, Huang Y, Srivastava D. (2013) Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning. Dev. Biol. 373:149–162. [PDF - 3.2 MB]
  147. Wamstad JA, Alexander JM, Truty RM, Shrikumar A, Li F, Eilertson KE, Ding H, Wylie JN, Pico AR, Capra JA, Erwin G, Kattman SJ, Keller GM, Srivastava D, Levine SS, Pollard KS, Holloway AK, Boyer LA, Bruneau BG. (2012) Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell151:206–220.
  148. Farina NH, Hausburg M, Dalla Betta N, Pulliam C, Srivastava D, Cornelison DD, Olwin BB. (2012) A role for RNA post-transcriptional regulation in satellite cell activation. Skelet. Muscle. 2:21.
  149. Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. (2012) Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 11:607–614.
  150. White MP, Rufaihah AJ, Liu L, Ghebremariam YT, Ivey KN, Cooke JP, Srivastava D. (2013) Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells 31:92–103.[PDF - 1.4 MB]
  151. Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I. (2013) Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells. Stem Cells Transl. Med. 2:161–166.[PDF - 5.3 MB]
  152. Ivey KN, Srivastava D. (2013) MicroRNAs as developmental regulators. In: Tam PPL, Nelson WJ, Rossant J, eds. Mammalian Development: Networks, Switches, and Morphogenetic Processes. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 33–42.
  153. Qian L, Srivastava D. Direct cardiac reprogramming: From developmental biology to cardiac regeneration. Circ. Res. 113:915-21.[PDF - 890 KB]
  154. Qian L, Berry EC, Fu JD, Ieda M, Srivastava D. (2013) Reprogramming of mouse fibroblasts to cardiomyocyte-like cells in vitro. Nature Protocols. 8:1204–1215.
  155. Srivastava D, Metzler KRC. (2013) Fending for a Braveheart. EMBO J. 32:1211–1213.
  156. Cheng P, Andersen P, Hassel D, Kaynak BL, Limphong P, Juergensen L, Kwon C, Srivastava D. (2013) Fibronectin mediates mesendodermal cell fate decisions. Development 140:2587–2596.
  157. Srivastava D, Heidersbach AJ. (2013) Small solutions to big problems: MicroRNAs for cardiac regeneration. Circ. Res. 112:1412–1414.
  158. Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR. (2013) AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy. PLoS ONE 8:e62705.
  159. Srivastava D, Berry EC. (2013) Cardiac reprogramming: From mouse toward man. Curr. Opin. Genet. Dev. 23:574–578.
  160. Fu J, Stone NR, Liu L, Spencer CI, Qian L, Hayashi Y, Delgado-Olguin P, Ding S, Bruneau BG, Srivastava D. (2013) Direct reprogramming of human fibroblasts toward the cardiomyocyte lineage. Stem Cell Reports 1:235–247.
  161. Heidersbach A, Saxby C, Carver-Moore K, Huang Y, Ang Y, de Jong PJ, Ivey KN, Srivastava D. (2013) microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. eLife. 2:e01323.
  162. Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K, Narita M, Srivastava D, Yamanaka S. (2014) The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of pro-differentiation genes. Cell Stem Cell 14:40–52.[PDF - 3.3 MB]
  163. Bruneau BG, Srivastava D. (2014) Congenital heart disease: Entering a new era of human genetics. Circ. Res. 114:598–599.[PDF - 462 KB]
  164. Wang H, Cao N, Spencer CI, Nie B, Ma T, Xu T, Zhang Y, Wang X, Srivastava D, Ding S. (2014) Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor. Cell Reports 6:951–960.
  165. Hu H, Roach JC, Coon H, Guthery SL, Voelkerding KV, Margraf RL, Durtschi JD, Tavtigian SV, Shankaracharya, Wu W, Scheet P, Wang S, Xing J, Glusman G, Hubley R, Li H, Garg V, Moore B, Hood L, Galas DJ, Srivastava D, Reese MG, Jorde LB, Yandell M, Huff CD. (2014) A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. Nat. Biotechnol. 32:663–669.[PDF - 1.6 MB]
  166. King I, Yartseva V, Salas D, Kumar A, Heidersbach A, Ando DM, Stallings NR, Elliott JL, Srivastava D, Ivey KN. (2014) The RNA binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-Induced Silencing Complex. J. Biol. Chem. 289:14263–14271.[PDF - 1.9 MB]
  167. Hua LL, Vedantham V, Barnes RM, Hu J, Robinson AS, Bressan M, Srivastava D, Black BL. (2014) Specification of the mouse cardiac conduction system in the absence of Endothelin signaling. Dev. Biol. 393:245–254.
    [PDF - 9.6 MB]
  168. Ang YS, Srivastava D. (2014) Oxygen: Double-edged sword in cardiac function and repair. Circ. Res. 115:824–825.[PDF - 563 KB]
  169. Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H. (2015) Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum. Mol. Genet. 24:424–435.
  170. Fu J, Srivastava D. (2015) Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine. Circ. J. 79:245–254.
  171. Vedantham V, Galang G, Evangelista M, Deo RC, Srivastava D. (2015) RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells. Circ. Res. 116:797–803.
  172. Theodoris CV, Li M, White MP, Liu L, He D, Pollard KS, Bruneau BG, Srivastava D. (2015) Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency. Cell 160:1072–1086.
  173. Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO. (2015) Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses. PLoS One 10:e0121765.
  174. White MP, Theodoris CV, Liu L, Collins WJ, Blue KW, Lee JH, Meng X, Robbins RC, Ivey KN, Srivastava D. (2015) NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium. J. Mol. Cell. Cardiol. 84:13–23.
  175. Ivey KN, Srivastava D. (2015) microRNAs as developmental regulators. Cold Spring Harb. Perspect. Biol. 7:a008144.
  176. Ribeiro AJS, Ang YS, Fu J-D, Rivas RN, Mohamed TMA, Higgs GC, Srivastava D, Pruitt BL. (2015) Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness. Proc. Natl. Acad. Sci. USA. do1:10.1073/pnas.1508073112
  177. Kime C, Rand TA, Ivey KN, Srivastava D, Yamanaka S, Tomoda K. (2015) Practical integration-free episomal methods for generating human induced pluripotent stem cells. Curr. Protoc. Hum. Genet. 87:21.22.21–21.22.21.
  178. Srivastava D, Yu P. (2015) Recent advances in direct cardiac reprogramming. Curr. Opin. Genet. Dev. 34:77–81.
  179. Gifford CA, Srivastava D. (2015) Heart disease modeling adds a Notch to its belt. Nat. Cell Biol. 18:3–5.
  180. Kime C, Mandegar MA, Srivastava D, Yamanaka S, Conklin BR, Rand TA. (2016) Efficient CRISPR/Cas9-based genome engineering in human pluripotent stem cells. Curr. Protoc. Hum. Genet. 88:21.4.1–21.4.23.
  181. Zhang Y, Cao N, Huang Y, Spencer CI, Fu JD, Yu C, Liu K, Nie B, Xu T, Li K, Xu S, Bruneau BG, Srivastava D, Ding S. (2016) Expandable cardiovascular progenitor cells reprogrammed from fibroblasts. Cell Stem Cell. 18:368–381.
  182. Cao N, Huang Y, Zheng J, Spencer CI, Zhang Y, Fu J-D, Nie B, Xie M, M Zhang, Wang H, Ma T, Xu T, Shi G, Srivastava D, Ding S. (2016) Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science. 352:1216–1220.
  183. Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge LM, Mandegar MA, C BF, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR. (2016) Miniaturized iPS-cell-derived cardiac muscles for physiologically relevant drug response analyses. Sci. Rep. 6:24726.
  184. Haldar SM, Srivastava D. (2016) Sarcomeres and cardiac growth: Tension in the relationship. Trends Mol. Med. 22:530–533.
  185. Sia J, Yu P, Srivastava D, Li S. (2016) Effect of biophysical cues on reprogramming to cardiomyocytes. Biomaterials. 103:1–11.
  186. Barruet E, Morales BM, Lwin W, White MP, Theodoris CV, Kim H, Urrutia A, Wong SA, Srivastava D, Hsiao EC. (2016) The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. Stem Cell Res. Ther. 7:115.
  187. Srivastava D, DeWitt N. (2016) In vivo cellular reprogramming: The next generation. Cell. 166:1386–1396.
  188. Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. (2016) The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nat. Med. 22:1131–1139.
  189. Ang YS, Rivas RN, Ribeiro AJS, Srivas R, Rivera J, Stone NR, Pratt K, Mohamed TMA, Fu J-D, Spencer CI, Tippens ND, Li M, Narasimha A, Radzinsky E, Moon-Grady AJ, Yu H, Pruitt BL, Snyder M, Srivastava D. (2016) Disease model of GATA4 mutation reveals transcription factor cooperativity in human cardiogenesis. Cell. 167:1734–1749.
  190. Mohamed TMA, Stone NR, Berry EC, Radzinsky E, Huang Y, Pratt K, Ang YS, Yu P, Wang H, Tang S, Magnitsky S, Ding S, Ivey KN, Srivastava D. (2017) Chemical enhancement of in vitro and in vivo direct cardiac reprogramming. Circulation. 135:978–995.
  191. Zhu JY, Heidersbach A, Kathiriya IS, Garay BI, Ivey KN, Srivastava D, Han Z, King IN. (2017) The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development. 144:866–875.
  192. Theodoris CV, Mourkioti F, Huang Y, Ranade SS, Liu L, Blau HM, Srivastava D. (2017) Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. J. Clin. Invest. 127:1683–1688.
  193. Ribeiro AJS, Schwab O, Mandegar MA, Ang YS, Conklin BR, Srivastava D, Pruitt BL. (2017) Multi-imaging method to assay the contractile mechanical output of micropatterned human iPSC-derived cardiac myocytes. Circ. Res. 120:1572–1583.
  194. Duan Q, McMahon S, Anand P, Shah H, Thomas S, Salunga HT, Huang Y, Zhang R, Sahadevan A, Lemieux ME, Brown JD, Srivastava D, Bradner JE, McKinsey TA, Haldar SM. (2017) BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure. Sci. Transl. Med. In press.

Last updated July 13, 2017


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