Wen WY, Ingerman E, Hansen MMK, Razooky BS, Dar RD, Chin C, Simpson ML, Weinberger LS.  In Press.  A Feedback Motif that Breaks Fundamental Limits on Noise Suppression to Stabilize Fate.. Cell.
Hansen MMK, Wen WY, Ingerman E, Razooky BS, Thompson CE, Dar RD, Chin CW, Simpson ML, Weinberger LS.  2018.  A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization.. Cell. 173(7):1609-1621.e15.
Pai A, Weinberger LS.  2017.  Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets.. Annu Rev Virol. 4(1):469-490.
Razooky BS, Cao Y, Hansen MMK, Perelson AS, Simpson ML, Weinberger LS.  2017.  Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.. PLoS Biol. 15(10):e2000841.
Saykally VR, Rast LI, Sasaki J, Jung S-Y, Bolovan-Fritts C, Weinberger LS.  2017.  A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus.. Bio Protoc. 7(21)
Aull KH, Tanner EJ, Thomson M, Weinberger LS.  2017.  Transient Thresholding: A Mechanism Enabling Noncooperative Transcriptional Circuitry to Form a Switch.. Biophys J. 112(11):2428-2438.
Ali I, Ramage H, Boehm D, Dirk LMA, Sakane N, Hanada K, Pagans S, Kaehlcke K, Aull K, Weinberger LS et al..  2016.  The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7.. J Biol Chem. 291(31):16240-8.
Rast LI, Rouzine IM, Rozhnova G, Bishop L, Weinberger AD, Weinberger LS.  2016.  Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals.. PLoS Comput Biol. 12(5):e1004799.
Tanner EJ, Kirkegaard KA, Weinberger LS.  2016.  Exploiting Genetic Interference for Antiviral Therapy.. PLoS Genet. 12(5):e1005986.
Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS.  2016.  Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels.. PLoS One. 11(7):e0158298.
Razooky BS, Pai A, Aull K, Rouzine IM, Weinberger LS.  2015.  A hardwired HIV latency program.. Cell. 160(5):990-1001.
Rouzine IM, Weinberger AD, Weinberger LS.  2015.  An evolutionary role for HIV latency in enhancing viral transmission.. Cell. 160(5):1002-1012.
Jung S-Y, Notton T, Fong E, Shusteff M, Weinberger LS.  2015.  Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting.. Lab Chip. 15(4):1000-3.
Weinberger LS.  2015.  A minimal fate-selection switch.. Curr Opin Cell Biol. 37:111-8.
Dar RD, Razooky BS, Weinberger LS, Cox CD, Simpson ML.  2015.  The Low Noise Limit in Gene Expression.. PLoS One. 10(10):e0140969.
Rouzine IM, Razooky BS, Weinberger LS.  2014.  Stochastic variability in HIV affects viral eradication.. Proc Natl Acad Sci U S A. 111(37):13251-2.
Fong EJ, Johnston AC, Notton T, Jung S-Y, Rose KA, Weinberger LS, Shusteff M.  2014.  Acoustic focusing with engineered node locations for high-performance microfluidic particle separation.. Analyst. 139(5):1192-200.
Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS.  2014.  Screening for noise in gene expression identifies drug synergies.. Science. 344(6190):1392-6.
Rouzine IM, Coffin JM, Weinberger LS.  2014.  Fifteen years later: hard and soft selection sweeps confirm a large population number for HIV in vivo.. PLoS Genet. 10(2):e1004179.
Notton T, SardanyĆ©s J, Weinberger AD, Weinberger LS.  2014.  The case for transmissible antivirals to control population-wide infectious disease.. Trends Biotechnol. 32(8):400-5.
Weinberger AD, Weinberger LS.  2013.  Stochastic fate selection in HIV-infected patients.. Cell. 155(3):497-9.
Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li P-C, Planelles V, Bradner JE et al..  2013.  BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.. Cell Cycle. 12(3):452-62.
Rouzine IM, Weinberger LS.  2013.  Design requirements for interfering particles to maintain coadaptive stability with HIV-1.. J Virol. 87(4):2081-93.
Gardner TJ, Bolovan-Fritts C, Teng MW, Redmann V, Kraus TA, Sperling R, Moran T, Britt W, Weinberger LS, Tortorella D.  2013.  Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies.. Clin Vaccine Immunol. 20(4):540-50.
Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS.  2012.  Transcriptional burst frequency and burst size are equally modulated across the human genome.. Proc Natl Acad Sci U S A. 109(43):17454-9.
Razooky BS, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger LS.  2012.  Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes.. Lab Chip. 12(21):4305-12.
Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS.  2012.  An endogenous accelerator for viral gene expression confers a fitness advantage.. Cell. 151(7):1569-80.
Singh A, Razooky BS, Dar RD, Weinberger LS.  2012.  Dynamics of protein noise can distinguish between alternate sources of gene-expression variability.. Mol Syst Biol. 8:607.
Metzger VT, Lloyd-Smith JO, Weinberger LS.  2011.  Autonomous targeting of infectious superspreaders using engineered transmissible therapies.. PLoS Comput Biol. 7(3):e1002015.
Franz K, Singh A, Weinberger LS.  2011.  Lentiviral vectors to study stochastic noise in gene expression.. Methods Enzymol. 497:603-22.
Singh A, Razooky B, Cox CD, Simpson ML, Weinberger LS.  2010.  Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression.. Biophys J. 98(8):L32-4.
Weinberger AD, Perelson AS, Ribeiro RM, Weinberger LS.  2009.  Accelerated immunodeficiency by anti-CCR5 treatment in HIV infection.. PLoS Comput Biol. 5(8):e1000467.
Singh A, Weinberger LS.  2009.  Stochastic gene expression as a molecular switch for viral latency.. Curr Opin Microbiol. 12(4):460-6.
Weinberger LS, Dar RD, Simpson ML.  2008.  Transient-mediated fate determination in a transcriptional circuit of HIV.. Nat Genet. 40(4):466-70.
Weinberger LS, Shenk T.  2007.  An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer.. PLoS Biol. 5(1):e9.
Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV.  2005.  Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity.. Cell. 122(2):169-82.
Weinberger LS, Schaffer DV, Arkin AP.  2003.  Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection.. J Virol. 77(18):10028-36.
Rosen HR, Ribeiro RR, Weinberger LS, Wolf S, Chung M, Gretch DR, Perelson AS.  2002.  Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy.. J Hepatol. 37(1):124-30.
Mohri H, Perelson AS, Tung K, Ribeiro RM, Ramratnam B, Markowitz M, Kost R, Hurley A, Weinberger LS, Cesar D et al..  2001.  Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy.. J Exp Med. 194(9):1277-87.
Shiratori Y, Perelson AS, Weinberger LS, Imazeki F, Yokosuka O, Nakata R, Ihori M, Hirota K, Ono N, Kuroda H et al..  2000.  Different turnover rate of hepatitis C virus clearance by different treatment regimen using interferon-beta.. J Hepatol. 33(2):313-22.
Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, Irwin CE, Safrit JT, Mittler J, Weinberger LS et al..  1999.  Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.. J Exp Med. 189(6):991-8.

Hansen MMK, Weinberger LS. Post-Transcriptional Noise Control. Bioessays. 2019 Jul; 41(7):e1900044.

Hansen MMK, Desai RV, Simpson ML, Weinberger LS. Cytoplasmic Amplification of Transcriptional Noise Generates Substantial Cell-to-Cell Variability. Cell Syst. 2018 Oct 24; 7(4):384-397.e6.

Vardi N, Chaturvedi S, Weinberger LS. Feedback-mediated signal conversion promotes viral fitness. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):E8803-E8810.

Hansen MMK, Wen WY, Ingerman E, Razooky BS, Thompson CE, Dar RD, Chin CW, Simpson ML, Weinberger LS. A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization. Cell. 2018 06 14; 173(7):1609-1621.e15.

Saykally VR, Rast LI, Sasaki J, Jung SY, Bolovan-Fritts C, Weinberger LS. A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus. Bio Protoc. 2017 Nov 05; 7(21).

Razooky BS, Cao Y, Hansen MMK, Perelson AS, Simpson ML, Weinberger LS. Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean. PLoS Biol. 2017 Oct; 15(10):e2000841.

Pai A, Weinberger LS. Fate-Regulating Circuits in Viruses: From Discovery to New Therapy Targets. Annu Rev Virol. 2017 09 29; 4(1):469-490.

Aull KH, Tanner EJ, Thomson M, Weinberger LS. Transient Thresholding: A Mechanism Enabling Noncooperative Transcriptional Circuitry to Form a Switch. Biophys J. 2017 Jun 06; 112(11):2428-2438.

Dar RD, Shaffer SM, Singh A, Razooky BS, Simpson ML, Raj A, Weinberger LS. Transcriptional Bursting Explains the Noise-Versus-Mean Relationship in mRNA and Protein Levels. PLoS One. 2016; 11(7):e0158298.

Ali I, Ramage H, Boehm D, Dirk LM, Sakane N, Hanada K, Pagans S, Kaehlcke K, Aull K, Weinberger L, Trievel R, Schnoelzer M, Kamada M, Houtz R, Ott M. The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7. J Biol Chem. 2016 07 29; 291(31):16240-8.

Rast LI, Rouzine IM, Rozhnova G, Bishop L, Weinberger AD, Weinberger LS. Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals. PLoS Comput Biol. 2016 05; 12(5):e1004799.

Tanner EJ, Kirkegaard KA, Weinberger LS. Exploiting Genetic Interference for Antiviral Therapy. PLoS Genet. 2016 05; 12(5):e1005986.

Weinberger LS. A minimal fate-selection switch. Curr Opin Cell Biol. 2015 Dec; 37:111-8.

Dar RD, Razooky BS, Weinberger LS, Cox CD, Simpson ML. The Low Noise Limit in Gene Expression. PLoS One. 2015; 10(10):e0140969.

Razooky BS, Pai A, Aull K, Rouzine IM, Weinberger LS. A hardwired HIV latency program. Cell. 2015 Feb 26; 160(5):990-1001.

Rouzine IM, Weinberger AD, Weinberger LS. An evolutionary role for HIV latency in enhancing viral transmission. Cell. 2015 Feb 26; 160(5):1002-1012.

Jung SY, Notton T, Fong E, Shusteff M, Weinberger LS. Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting. Lab Chip. 2015 Feb 21; 15(4):1000-3.

Rouzine IM, Razooky BS, Weinberger LS. Stochastic variability in HIV affects viral eradication. Proc Natl Acad Sci U S A. 2014 Sep 16; 111(37):13251-2.

Notton T, SardanyƩs J, Weinberger AD, Weinberger LS. The case for transmissible antivirals to control population-wide infectious disease. Trends Biotechnol. 2014 Aug; 32(8):400-5.

Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS. Screening for noise in gene expression identifies drug synergies. Science. 2014 Jun 20; 344(6190):1392-6.

Rouzine IM, Coffin JM, Weinberger LS. Fifteen years later: hard and soft selection sweeps confirm a large population number for HIV in vivo. PLoS Genet. 2014 Feb; 10(2):e1004179.

Fong EJ, Johnston AC, Notton T, Jung SY, Rose KA, Weinberger LS, Shusteff M. Acoustic focusing with engineered node locations for high-performance microfluidic particle separation. Analyst. 2014 Mar 07; 139(5):1192-200.

Weinberger AD, Weinberger LS. Stochastic fate selection in HIV-infected patients. Cell. 2013 Oct 24; 155(3):497-9.

Rouzine IM, Weinberger LS. Reply to "Coadaptive stability of interfering particles with HIV-1 when there is an evolutionary conflict". J Virol. 2013 Sep; 87(17):9960-2.

Gardner TJ, Bolovan-Fritts C, Teng MW, Redmann V, Kraus TA, Sperling R, Moran T, Britt W, Weinberger LS, Tortorella D. Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies. Clin Vaccine Immunol. 2013 Apr; 20(4):540-50.

Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS. An endogenous accelerator for viral gene expression confers a fitness advantage. Cell. 2012 Dec 21; 151(7):1569-80.

Rouzine IM, Weinberger LS. Design requirements for interfering particles to maintain coadaptive stability with HIV-1. J Virol. 2013 Feb; 87(4):2081-93.

Razooky BS, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger LS. Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes. Lab Chip. 2012 Nov 07; 12(21):4305-12.

Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS. Transcriptional burst frequency and burst size are equally modulated across the human genome. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17454-9.

Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle. 2013 Feb 01; 12(3):452-62.

Singh A, Razooky BS, Dar RD, Weinberger LS. Dynamics of protein noise can distinguish between alternate sources of gene-expression variability. Mol Syst Biol. 2012; 8:607.

Metzger VT, Lloyd-Smith JO, Weinberger LS. Autonomous targeting of infectious superspreaders using engineered transmissible therapies. PLoS Comput Biol. 2011 Mar; 7(3):e1002015.

Franz K, Singh A, Weinberger LS. Lentiviral vectors to study stochastic noise in gene expression. Methods Enzymol. 2011; 497:603-22.

Razooky BS, Weinberger LS. Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise. Methods. 2011 Jan; 53(1):68-77.

Singh A, Razooky B, Cox CD, Simpson ML, Weinberger LS. Transcriptional bursting from the HIV-1 promoter is a significant source of stochastic noise in HIV-1 gene expression. Biophys J. 2010 Apr 21; 98(8):L32-4.

Weinberger AD, Perelson AS, Ribeiro RM, Weinberger LS. Accelerated immunodeficiency by anti-CCR5 treatment in HIV infection. PLoS Comput Biol. 2009 Aug; 5(8):e1000467.

Singh A, Weinberger LS. Stochastic gene expression as a molecular switch for viral latency. Curr Opin Microbiol. 2009 Aug; 12(4):460-6.

Weinberger LS, Dar RD, Simpson ML. Transient-mediated fate determination in a transcriptional circuit of HIV. Nat Genet. 2008 Apr; 40(4):466-70.

Weinberger LS, Shenk T. An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer. PLoS Biol. 2007 Jan; 5(1):e9.

Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell. 2005 Jul 29; 122(2):169-82.

Weinberger LS, Schaffer DV, Arkin AP. Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection. J Virol. 2003 Sep; 77(18):10028-36.

Rosen HR, Ribeiro RR, Weinberger L, Wolf S, Chung M, Gretch DR, Perelson AS. Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy. J Hepatol. 2002 Jul; 37(1):124-30.

Mohri H, Perelson AS, Tung K, Ribeiro RM, Ramratnam B, Markowitz M, Kost R, Hurley A, Weinberger L, Cesar D, Hellerstein MK, Ho DD. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med. 2001 Nov 05; 194(9):1277-87.

Shiratori Y, Perelson AS, Weinberger L, Imazeki F, Yokosuka O, Nakata R, Ihori M, Hirota K, Ono N, Kuroda H, Motojima T, Nishigaki M, Omata M. Different turnover rate of hepatitis C virus clearance by different treatment regimen using interferon-beta. J Hepatol. 2000 Aug; 33(2):313-22.

Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, Irwin CE, Safrit JT, Mittler J, Weinberger L, Kostrikis LG, Zhang L, Perelson AS, Ho DD. Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques. J Exp Med. 1999 Mar 15; 189(6):991-8.