Research Interests

Jennifer Doudna’s laboratory focuses on using CRISPR technologies to study molecular mechanisms of disease and establish first-of-their-kind genome surgery approaches to treat disease by cutting out or modifying harmful DNA. 

Her team is working toward generating novel curative treatments for genetic disorders, beginning with neurodegenerative disorders and diseases of the eye. They are also using CRISPR technology to better understand the genetics of certain cancers like glioblastoma. Ultimately, they hope to find new therapeutic targets to probe the genes that these cancers become dependent upon.