- American Neurological Association
Our laboratory studies mechanisms of neurovascular regulation in inflammation and tissue repair. Our current research focuses on identifying the molecular and cellular interface that blood proteins use to interact with and change the functions of cells in the nervous system. When this vasculature—the blood-brain barrier (BBB)—ruptures, blood proteins can enter into the brain and cause edema and neuronal damage in a variety of neurological diseases, such as stroke, multiple sclerosis, Alzheimer's disease, and spinal cord injury. We aim to unravel the molecular mechanisms of the central nervous system’s (CNS) response to neurovascular changes, with the ultimate goal to develop novel therapeutic strategies for neurological diseases.