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Recent Advances

December 2, 2014

SAN FRANCISCO and NEW YORK—Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3.

November 12, 2014

SAN FRANCISCO—In the fight against HIV, microbicides—chemical compounds that can be applied topically to the female genital tract to protect against sexually transmitted infections—have been touted as an effective alternative to condoms. 

June 5, 2014

SAN FRANCISCO, CA—A team of scientists at the Gladstone Institutes has identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection.

December 19, 2013

SAN FRANCISCO, CA—Research led by scientists at the Gladstone Institutes has identified the precise chain of molecular events in the human body that drives the death of most of the immune system’s CD4 T cells as an HIV infection leads to AIDS.

December 18, 2013

SAN FRANCISCO, CA—In 2012 the HIV antiretroviral drug Truvada became the first and only medication approved by the FDA for HIV prevention.

November 7, 2013

SAN FRANCISCO, CA—One of biology’s most fundamental processes is something called transcription. It is just one step of many required to build proteins—and without it life would not exist. However, many aspects of transcription remain shrouded in mystery.

October 30, 2013

SAN FRANCISCO, CA—Perhaps the single greatest barrier to curbing the spread of HIV/AIDS is the dormant, or “latent,” reservoir of virus, which is out of reach of even the most potent medications.

September 30, 2013

SAN FRANCISCO, CA—Three Gladstone scientists have won research awards from divisions of the National Institutes of Health (NIH) equaling an approximate total of $12.5 million over five years for their groundbreaking research to overcome HIV/AIDS.

December 20, 2012

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have mapped the molecular mechanism by which a virus known as cytomegalovirus (CMV) so successfully infects its hosts.

December 6, 2012

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have identified a novel mechanism by which a type of low-carb, low-calorie diet—called a “ketogenic diet”—could delay the effects of aging.