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The Sanjabi Lab aims to understand how protective innate and adaptive immune responses are elicited and maintained upon mucosal transmission of viral pathogens. More specifically, we study how viral pathogens are transmitted via genital mucosa, how various antigen-presenting cells (APCs) sense the virus, and how APC activation contributes to priming, differentiation, trafficking, and formation of protective memory CD8 T cells. We utilize model and emerging human pathogens, together with various mouse genetic models and a combination of cellular, molecular, flow cytometric and immunohistochemical approaches to study pathogen specific anti-viral immune responses.
- Microbiology and Molecular Genetics
- University of California, Los Angeles
- Microbiology, Immunology, and Molecular Genetics
- "University of California, Los Angeles"
- Yale University