Seth Shipman, PhD
Assistant Investigator, Gladstone Institute of Data Science and Biotechnology

Phone

(415) 734-4058

Assistant

Sue Cammack
(415) 734-2713

Areas of Investigation

Shipman’s laboratory is broadly interested in engineering new functions into living cells. Recently, they developed a novel method to record information into the DNA of cells with molecular recording devices. These can be used to better understand the molecular timing of developing systems and to create living molecular diagnostics compatible with long-term monitoring of in vivo physiology.

Shipman’s team also aims to engineer arbitrary neural circuits from the ground up using human stem cell–derived neurons as the building material. From simple circuits, they hope to discover the fundamental molecular rules that govern connectivity in the brain. This understanding will be critical to solving neurodevelopment and neuropsychiatric disease.

Lastly, Shipman’s laboratory is interested in engineering synthetic organelles like mitochondria to extend the capacity of eukaryotic cells. This approach will provide new insight into the fundamental biology of developing systems, and may lead to new methods to treat diseases of degeneration and aging. 

Education

2005
BA
  • Wesleyan Univertisy
2012
PhD
  • University of California San Francisco

Honors and Awards

2019 Bridge to Independence Award, Simons Foundation Autism Research Initiative
2018 DARPA Riser, DARPA 60th Anniversary Symposium
2014 Life Sciences Research Foundation Postdoctoral Fellowship, Shurl and Kay Curci Foundation
2012 Gorden Research Outstanding Poster Award, Molecular and Cellular Neurobiology