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Dr. Paz studies epileptogenesis, the process by which a normal brain develops epilepsy. Epilepsy occurs in a number of neurological diseases; however, the underlying mechanisms of the condition are not well understood. While many antiepileptic drugs exist, they often have side effects and cannot fully suppress the highly disruptive and potentially fatal symptoms seen in patients with epilepsy. Dr. Paz seeks to improve this situation by investigating how epileptic activity is initiated and maintained. She is exploring new strategies that block the pathogenic loops that can emerge between the cortical and subcortical brain regions in epileptic models.
Dr. Paz earned her undergraduate and graduate degrees from the University Pierre et Marie Curie in Paris. As a graduate student, she studied the role of basal ganglia in regulating absence epilepsy and received an award for the best neuroscience PhD thesis in France. Dr. Paz then completed a postdoctoral fellowship at Stanford, where she identified seizure control points in the brain.