SAN FRANCISCO, CA—In a pair of new studies, Gladstone scientists discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson’s disease.
SAN FRANCISCO, CA—Study seeks to improve translation of Alzheimer’s disease studies with virtual version of the Morris water maze—the most commonly used memory assessment in mice.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells.
SAN FRANCISCO, CA—Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer’s disease.
SAN FRANCISCO, CA—A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS).
SAN FRANCISCO, CA—Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD).
SAN FRANCISCO, CA—A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria—the brain’s cellular power plants—can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative disease.
SAN FRANCISCO, CA—The Gladstone Institutes announces the creation of Cure Network Ventures Inc. and Cure Network Dolby Acceleration Partners, LLC, a business endeavor with Dolby Family Ventures and Evotec AG, which will focus on Alzheimer’s disease.
SAN FRANCISCO—Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully protected against cell death in both genetic and sporadic versions of the disease.
SAN FRANCISCO, CA—Scientists from the Gladstone Institutes and the University of California, San Francisco report in the Journal of Neuroscience that raising levels of the life-extending protein klotho can protect against learning and memory deficits in a mouse model of Alzheimer’s disease.