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Recent Advances

December 26, 2016

SAN FRANCISCO, CA—New details learned about a key cellular protein could lead to treatments for neurodegenerative diseases, such as Parkinson’s, Huntington’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS). 

September 8, 2016

SAN FRANCISCO, CA—Gladstone Senior Investigator Katerina Akassoglou, PhD, was awarded a prestigious multi-year, multi-million dollar grant from the National Institute of Neurological Disorders and Stroke (NINDS). 

August 15, 2016

SAN FRANCISCO, CA—There is new hope in the fight against Huntington’s disease. Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease. 

May 5, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered how the major genetic risk factor for Alzheimer’s disease causes memory impairment.

March 31, 2016

SAN FRANCISCO, CA—Scientists have long known that the protein tau is involved in dementia, but how it hinders cognitive function has remained uncertain. In a study published in the journal Neuron, researchers at the Gladstone Institutes reveal how tau disrupts the ability of brain cells to strengthen connections with other brain cells, preventing new memories from forming.

January 28, 2016

SAN FRANCISCO, CA—In a pair of new studies, Gladstone scientists discovered a specific neural circuit that controls walking, and they found that input to this circuit is disrupted in Parkinson’s disease.

January 19, 2016

SAN FRANCISCO, CA—Study seeks to improve translation of Alzheimer’s disease studies with virtual version of the Morris water maze—the most commonly used memory assessment in mice.

January 12, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered an unusual regulator of body weight and the metabolic syndrome: a molecular mechanism more commonly associated with brain cells.

November 30, 2015

SAN FRANCISCO, CA—Researchers from the Gladstone Institutes have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer’s disease.

October 9, 2015

SAN FRANCISCO, CA—A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS).