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Recent Advances

November 10, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified two chemicals that improve their ability to transform scar tissue in a heart into healthy, beating heart muscle. The new discovery advances efforts to find new and effective treatments for heart failure.

October 21, 2016

SAN FRANCISCO, CA—How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation. 

September 25, 2016

SAN FRANCISCO, CA—Stem cell experts will discuss the future of cellular reprogramming and its therapeutic potential at the Cell Symposium “10 Years of iPSCs,” September 25–27, 2016 at the Claremont Hotel and Spa in Berkeley, Califo

August 4, 2016

SAN FRANCISCO, CA—With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection.

April 28, 2016

SAN FRANCISCO, CA—In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.

March 10, 2016

SAN FRANCISCO, CA—Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation of the CRISPR-Cas9 system.

February 11, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that three transcription factors—proteins that direct gene expression—interact with each other and the genome to influence how a heart forms in an embryo.

January 6, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully converted human skin cells into fully-functional pancreatic cells.

November 23, 2015

SAN FRANCISCO, CA—Scientists have revealed that glucocorticoids, a class of steroid hormones that are commonly prescribed as drugs, enhance muscle endurance and alleviate muscular dystrophy through activation of the gene KLF15.

July 14, 2015

SAN FRANCISCO, CA—Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells, creating a system that could serve as a model for early heart development and a drug-screening tool to make pregnancies safer.

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