Scientists discover how to identify off-target damage caused by CRISPR genome editing
New discoveries about how cells self-organize could help researchers create more authentic organ models for research or transplantation
Researchers at the Gladstone Institutes provide answers to decade-old questions
Gladstone scientists identify genes that enable adult cells to divide and multiply
Activating a single gene is sufficient to change skin cells into stem cells
The discovery could improve treatments for autoimmune diseases and cancer
SAN FRANCISCO, CA—After decades of research aiming to understand how DNA is organized in human cells, scientists at the Gladstone Institutes have shed new light on this mysterious field by discovering how a key protein helps control gene organization.
SAN FRANCISCO, CA—A team of researchers at the Gladstone Institutes uncovered a new strategy to treat heart failure, a leading contributor to mortality and healthcare costs in the United States.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit signals in the spinal cord to help control movement.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and less body weight gain, even after being fed a high-calorie diet.