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Gladstone scientists discover how the novel coronavirus damages heart muscle cells, and create a system that can be used to screen potential therapies
News Release Research (Publication) COVID-19 Cardiovascular Disease Virology Conklin Lab McDevitt Lab Ott Lab
Two Gladstone scientist share their recent COVID-19 research
COVID-19 Conklin Lab McDevitt Lab
The Guardian—Recent work from Senior Investigators Todd McDevitt, PhD, and Bruce Conklin, MD, documenting the damaging effect of SARS-CoV-2 on heart cells is mentioned in a detailed review of the long-term impact of COVID-19 on patients’ hearts.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
Ken Nakamura and Todd McDevitt will study how to boost cells’ energy and how the strategy can best treat disease
Grants Cardiovascular Disease Neurological Disease McDevitt Lab Nakamura Lab
The Wall Street Journal—Senior Investigator Todd McDevitt, PHD, comments on the damage SARS-CoV-2 can inflict on heart cells, which he and Senior Investigator Bruce Conklin, MD, recently reported in an article deposited on bioRxiv.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
The New Indian Express—The New Indian Express integrates the recent findings of Senior Investigators Todd McDevitt, PhD, and Bruce Conklin, MD, in an opinion piece about the effects of COVID-19 on the heart.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
Wired—In an article about the potential dangers of strenuous exercise for people who have been infected with SARS-CoV-2, Senior Investigator Bruce Conklin, MD, is quoted for likening to "carnage" the damage the virus can inflict on heart cells. Conklin and Senior Investigator Todd McDevitt, PhD, recently reported their observations of cardiac cells from deceased COVID-19 patients or grown in the lab in BioRxiv.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
The Times of India—The Times of India reports the recent discovery by Senior Investigators Todd McDevitt, PhD, and Bruce Conklin, MD, that SARS-CoV-2 can inflict severe damage to heart cells, and puts it in the context of several examples of cardiovascular failure in patients recovering from COVID-19 in India.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
The New Republic—Senior investigator Todd McDevitt, PhD, explains how his recent discovery that SARS-CoV-2 inflicts severe damage on heart cells could explain why some people experience symptoms of heart malfunction months after they recover from COVID-19. McDevitt stresses that COVID-19 is not just a respiratory disease, and could instead lead to permanent damage to various organs, even in young people.
Gladstone Experts COVID-19 Cardiovascular Disease McDevitt Lab
Yahoo! News—Some individuals who survive the initial bout with COVID-19 experience heart damage weeks or months later. Gladstone Investigator Todd McDevitt explains how his recent research shows that SARS-CoV-2 can devastate heart muscle cells, which could have long-term consequences for heart function.
Gladstone Experts COVID-19 Cardiovascular Disease McDevitt Lab
Live Science—Senior Investigators Todd McDevitt, PhD, and Bruce Conklin, MD, comment on their recent discovery that SARS-CoV-2 infects and destroys heart muscle cells grown in the lab and may do so in the hearts of COVID-19 patients as well.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
ABC7 News—As sports teams and colleges consider restarting the athletics season, Senior Investigator Todd McDevitt, PhD, and Gladstone President and Cardiologist Deepak Srivastava, MD, express concern that damage to the heart caused by SARS-CoV-2 infection could put athletes at risk for serious heart problems even if they only experienced mild COVID-19 symptoms.
Gladstone Experts COVID-19 Cardiovascular Disease McDevitt Lab Srivastava Lab
STAT—Senior Investigators Todd McDevitt, PhD, and Bruce Conklin, MD, comment on their recent findings of severe damage in cardiac cells exposed to SARS-CoV-2 in the lab and in the heart cells of deceased COVID-19 patients. They also explain why they felt the need to share these findings rapidly with the scientific community via the preprint publishing platform bioRxiv.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Conklin Lab McDevitt Lab
While many are working from home, these scientists are continuing to go to the lab in hopes of making a discovery that could lead to the end of the COVID-19 pandemic.
Gladstone Experts COVID-19 Cardiovascular Disease Data Science and Biotechnology Virology Conklin Lab McDevitt Lab Ott Lab
Science Cover—In addition to causing respiratory disease, COVID-19 can also affect the cardiovascular system, and indeed heart failure may be the cause of many COVID-19 deaths. At Gladstone, Senior Investigators Bruce Conklin and Todd McDevitt are using stem cell–derived heart cells and microtissues to investigate how COVID-19 affects heart cardiac function, and to identify new therapeutic targets.
Gladstone Experts COVID-19 Cardiovascular Disease iPS Cell Research Center Conklin Lab McDevitt Lab