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Systems and Synthetic Biology Symposium

Gladstone Center for Cell Circuitry
Tuesday, June 4, 2019 - 12:00pm to 5:00pm
Room 107A/B

From tiny viruses to complex organs, genetic circuits are fundamental to biology. Circuits connect individual molecular components and allow cells to process signals and control decision-making. Therapeutically, cellular circuits have enormous potential; if these circuits can be mapped, we could repair broken circuits that lead to disease and disrupt specialized circuits in viruses and cancers. The inaugural Gladstone Center for Cell Circuitry 2019 Systems and Synthetic Biology Symposium aims to bring together scientists exploiting gene circuits to answer biological questions from fundamental biology to therapeutics.


Lunch and Welcome—Leor Weinberger


Molecular Determinants of Transcriptional Variability in Development
Hernan Garcia, UC Berkeley


Cell Size–Based Decision-Making of a Viral Gene Circuit
Roy Dar, University of Illinois at Urbana-Champaign


Post-Transcriptional Noise Control: From Phenotypic Exploration to  Commitment
Maike Hansen, Gladstone Institutes, UCSF


Patterns of Early p21 Dynamics Determine Proliferation-Senescence Cell Fate after Chemotherapy
Charles (Chien-Hsiang) Hsu, UCSF


From Temporary to Sustained—A Positive Feedback Loop Enhances Viral Production
Noam Vardi, Gladstone Institutes, UCSF


Coffee Break


Gene Expression in Living and Non-Living Things
Cheemeng Tan, UC Davis


Emergence of Order in Small, Crowded, and Noisy Environments
Mike Simpson, Oak Ridge National Laboratory


Deciphering Cell States: The Relationship between Single-Cell Gene Expression and Phenotypic Heterogeneity in Calcium Signaling
Roy Wollman, UCLA


Nucleosomal Proofreading of Activator-Promoter Interactions
Hinrich Boeger, UC Santa Cruz


Reception in Gladstone Lobby


Hosted By: 

Gladstone Center for Cell Circuitry

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