Genome-Wide Approaches to Understanding Microglia Identity and Function
Chris Glass is a professor of cellular and molecular medicine and professor of medicine at UC San Diego. His current studies use a combination of genetics and genomics to define molecular mechanisms specifying transcriptional regulatory elements that establish macrophage identity and cell-specific responses to environmental signals. Glass’s lab is currently applying these approaches to understand pathological programs of macrophage gene expression that promote the development of atherosclerosis, diabetes, cancer, and neurodegenerative diseases.
Glass received his MD and PhD from UC San Diego and performed internship and residency training in internal medicine at Brigham and Women’s Hospital. He returned to UC San Diego for fellowship training in endocrinology and metabolism and then joined the UC San Diego faculty. Glass has had a long-standing interest in elucidating the molecular mechanisms by which sequence-specific transcription factors, co-activators, and co-repressors regulate the development and function of macrophages in health and disease.
A reception will follow the lecture.
Spectrum Seminars is a new series to bring together Gladstone scientists around topics that apply across fields of study.