“Network Abnormalities and Interneuron Dysfunction in Alzheimer’s Disease”
- Gladstone Science Talks
Jorge Palop, PhD
Jorge Palop’s group studies the neuronal processes underlying cognitive impairments in neurological and neuropsychiatric conditions associated with abnormal synchronization of neuronal networks, including Alzheimer’s disease (AD). His laboratory is currently focused on understanding the role of inhibitory interneurons in altered oscillatory brain rhythms, network hypersynchrony, and cognitive impairments in AD. Using mouse models, electrophysiology, and optogenetics, Palop’s team aims to identify cellular and circuit mechanisms of cognitive dysfunction and to develop novel therapeutic approaches to restore brain functions.