You are here

Science Talks Web Banner 2019

Neurovascular Interactions: Mechanisms, Imaging, and Therapeutics

Katerina Akassoglou, PhD, Senior Investigator
  • Gladstone Science Talks
Tuesday, October 22, 2019 - 11:00am to 12:00pm
Mahley Auditorium

Katerina Akassoglou and her team aim to understand the mechanisms that control communication between the brain, immune, and vascular systems. They pioneered studies showing that when the blood-brain barrier is disrupted, the blood-clotting factor fibrinogen can leak into the brain, where it inhibits myelin repair, activates immune responses, and induces neurodegeneration. They developed high-resolution in vivo imaging methods to image the neurovascular interface and a new therapeutic antibody to target the neuroinflammatory functions of fibrin. These mechanisms and therapeutic applications could contribute to a wide range of neurological conditions associated with blood-brain barrier disruption, demyelination, and microglial activation, such as Alzheimer’s disease, multiple sclerosis, and brain injury.

Gladstone Science Talks allow investigators to share the latest research from their laboratories. These talks are open to the broader Gladstone community. View all upcoming Gladstone Science Talks

Upcoming Events

Katerina Akassoglou, PhD, Senior Investigator
Tue, Oct 22, 2019 - 11:00am
Meet representatives from Sartorius
Wed, Oct 23, 2019 - 9:00am
Priti Kumar, PhD, Yale School of Medicine
Center for Cell Circuitry Seminar
Wed, Oct 23, 2019 - 12:00pm
Discover how the IncuCyte S3 can advance your research
Wed, Oct 23, 2019 - 12:30pm