Cell Mapping Symposium 2017
The 2017 Cell Mapping Symposium, hosted by Gladstone Institutes and the Quantitative Biosciences Institute (QBI) at UCSF, will address research and technology advances in cell mapping as it relates to cancer, psychiatric disorders, and infectious disease.
The ability of a cell to respond to its environment depends on the actions of the proteins encoded by the DNA in the genome. However, most proteins don’t work alone. They work with other proteins in teams called complexes. The principles of “cell mapping” are to figure out which proteins work together in complexes. Mapping can be done in different disease states or in the presence of different chemical drugs. To accomplish these goals, researchers augment these cell maps with genetic maps to derive quantitative insights into how biological functions of cells can be restored.
One of the main objectives of this symposium is to discuss technological advances in extracting mechanistic insight from these large genome sequencing projects. These efforts include using proteomic, biochemical, genetic, and structural biology approaches to generate cellular maps that can be used to interpret this genomic data from a variety of different disease areas.
The 2017 Cell Mapping Symposium, will be held over 2 days, September 13 and 14, 2017, at the Gladstone Institutes in San Francisco’s Mission Bay neighborhood. Confirmed speakers for the symposium are listed below.
Join us to find out more about this exciting topic.
Dave Agard, UCSF—“Using CryoEm to Understand Dynamic Protein Complexes”
Cori Bargmann, Chan-Zuckerberg Science
Michael Boutros, DKFZ—“Mapping Genetic Interaction Networks (in Cancer Cells)”
Jasmin Fisher, University of Cambridge and Microsoft Research—“Deconstructing Cancer Networks Using Executable Biology”
J, UC Berkeley
Jennifer Grandis, UCSF
Rick Horwitz, Allen Institute—“Integrated Spatial-Temporal Stem Cell Biology: A Next Step in the Post-Genomic Era”
Trey Ideker, UC San Diego
Martin Kampman, UCSF—“Mapping Neuronal Cell Biology in Health and Disease with CRISPRi and CRISPRa”
Nevan Krogan, UCSF and Gladstone Institutes
Kasper Lage, Massachusetts General Hospital, Stanley Center at the Broad Institute, and Harvard Medical School—“Large-Scale Protein-Protein Interaction Experiments of Schizophrenia Risk Genes in Human Neurons Coalesce GWAS Loci into Unexpected Pathways”
Joana Loizou, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences—“Rebalancing DNA Repair Pathways in Disease”
Clodagh O' Shea, Salk Institute
Teresa Przytycka, NCBI, NIH—“New Methods to Uncover Properties of Mutational Landscape in Cancer”
Ben Raphael, Princeton
Andrej Sali, UCSF—“Integrative Structural Biology”
Laura Van’t Veer, UCSF
Mark Von Zastrow, UCSF—“Spatiotemporal Dynamics of Protein Interaction Networks in Living Cells”
Gladstone Institutes and the Quantitative Biosciences Institute at UCSF