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News and Highlights

November 12, 2016
Drs. Mucke and Paz

Gladstone scientists discover how to control the cacophony of electrical activity in the brain, stopping seizures and reducing deficits related to Alzheimer’s disease.

November 10, 2016
Drs. Mohamed and Srivastava

Scientists at the Gladstone Institutes identified two chemicals that improve their ability to transform scar tissue in a heart into healthy, beating heart muscle. The discovery advances efforts to find new and effective treatments for heart failure.


October 25, 2016
Dr. Nevan Krogan

Researchers at the Gladstone Institutes and UCSF have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.


October 24, 2016
Drs. Bruce Conklin and Shinya Yamanaka

How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation.


October 17, 2016
Dr. Katerina Akassoglou

Katerina Akassoglou is calling for a fundamental change in the way scientists approach neurological disorders. Her research on the brain’s vascular and immune systems has led to new insights about multiple sclerosis and other conditions.

September 28, 2016
Dr. Douglas Melton

Melton was awarded the prize for his pioneering work to treat diabetes with stem cells. The award celebrates scientists whose original translational research has advanced cellular reprogramming technology for regenerative medicine.

September 1, 2016
Cells edited with CRISPRi

CRISPR has enormous potential to cure intractable diseases. At the Gladstone Institutes, scientists are using the technology to advance scientific knowledge and pursue new therapies for heart disease, HIV, dementia, blindness, and more.

August 18, 2016
Dr. Saptarsi Haldar

Taking inspiration from cancer research, Saptarsi Haldar investigates how to fix harmful gene expression in damaged heart cells.

August 15, 2016
Dr. Steve Finkbeiner

Changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

August 4, 2016
Josh Zimmerman and Todd McDevitt

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders.