Gladstone scientists discover how to control the cacophony of electrical activity in the brain, stopping seizures and reducing deficits related to Alzheimer’s disease.
News and Highlights
Scientists at the Gladstone Institutes identified two chemicals that improve their ability to transform scar tissue in a heart into healthy, beating heart muscle. The discovery advances efforts to find new and effective treatments for heart failure.
Researchers at the Gladstone Institutes and UCSF have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation.
Katerina Akassoglou is calling for a fundamental change in the way scientists approach neurological disorders. Her research on the brain’s vascular and immune systems has led to new insights about multiple sclerosis and other conditions.
Melton was awarded the prize for his pioneering work to treat diabetes with stem cells. The award celebrates scientists whose original translational research has advanced cellular reprogramming technology for regenerative medicine.
CRISPR has enormous potential to cure intractable diseases. At the Gladstone Institutes, scientists are using the technology to advance scientific knowledge and pursue new therapies for heart disease, HIV, dementia, blindness, and more.
Taking inspiration from cancer research, Saptarsi Haldar investigates how to fix harmful gene expression in damaged heart cells.
Changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.
With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders.