Researchers at the Gladstone Institutes are using healthy heart cells to repair and rejuvenate damaged hearts, a procedure that, if successful, could usher in a new era of gene therapy and heart treatment.
SF Business Times
Reprogrammed stem cells that Gladstone and UC Berkeley researchers prodded and poked to form a tiny chamber could hold the key to creating better, cheaper and safer heart drugs. "We're at the beginning of the IPS revolution," said Dr. Bruce Conklin.
Scientists are in hot pursuit of finding an efficient way to directly transform skin cells into other cell types in the body—skipping an intermediate pluripotent stem cell step. Dr. Sheng Ding, a pioneer in this field, weighs in on new research to directly transform skin cells to brain cells using a chemical cocktail.
Wall Street Journal
At the Gladstone Institutes, scientists are using advanced tissue-repair technologies like gene editing and induced pluripotent stem cells to reprogram cells in adult human hearts to allow them to rebuild damaged cardiac muscle.
Dolby Family Ventures is working with the Gladstone Institutes on an unusual plan to fund high-risk Alzheimer's treatments that are still in the early research stages.
Dr. Warner Greene says the girl - who was infected at birth but has been off medication for 12 years - may be an "elite responder." This means that even though she is technically still infected with the virus, her HIV levels are almost undetectable without medication, making her functionally cured.
Over the last 10 years, Alzheimer’s research has come a long way, yet there’s still no cure or way to slow down this complex disease. Dr. Lennart Mucke discusses the promising medical developments on the horizon.
By manipulating stem cells, scientists from the Gladstone Institutes and UC Berkeley have found they can grow beating cardiac tissue in a petri dish. The cells "self-organized" to form microchambers, which slowly began to beat like a full-sized heart.
Dr. Steven Finkbeiner is part of the Neurocollaborative, an initiative that is creating stem cell lines from ALS patients that will mimic their own nerve cells and received money from the Ice Bucket challenge.
Researchers have used stem cells to create a tiny, beating heart - and say it could revolutionise medicine. The new hearts will allow new drugs to be tested, and give researchers a new insight into how the heart develops.