A delay in the body’s immune response allows the virus to “hide,” and as a result increases the risk of fetal infection during pregnancy. The new discovery suggests that, when the virus is sexually transmitted, women are both more susceptible to catching the virus and have a harder time clearing it from their system.
Women are at greater risk for Zika infection than men, new research in mice suggests. Scientists found the virus appears to trigger a delay in the vagina's immune response.
Gladstone Institutes scientists have pinpointed two chemicals that help the heart convert scar tissue into healthy cardiac muscle. The discovery could lead to new treatments for heart failure, for which there is no cure.
A new method of cellular reprogramming has resulted in the generation of 8 times more heart cells and reduced the time needed for the process from 6 to 8 weeks to just 1 week. This new treatment has a long way to go before human trials, but it could one day result in better treatments for the millions of people suffering from heart disease.
A team at San Francisco's Gladstone Institutes tested 5,500 different chemicals before identifying two that help turn scar tissue into healthy heart muscle. The development could transform prospects for heart failure patients.
Scientists used CRISPR/Cas9 to test gene after gene after gene in human immune system cells—45 genes in all—to identify those that are involved with infection by the HIV virus.
Thanks to a chance discovery, researchers have found a more efficient way to create induced pluripotent stem cells (iPSCs), which are widely used in regenerative medicine research and drug development.
International Business Times
The innovative genome editing tool known as CRISPR-Cas9 could accelerate the search for an effective HIV cure, scientists say. They have used the technology to investigate whether specific genetic tweaks to immune cells' DNA could increase resistance to an HIV infection.
The powerful gene-editing tool CRISPR could hold the key to finally solving the AIDS crisis. The low-cost technology could allow us to transfer the gene mutations that make some people naturally resistant to HIV into other people’s immune cells, creating a potentially permanent cure for the virus.