Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), together with collaborators in Europe, discovered that a common type of cell within the human reproductive and intestinal tracts assists HIV in infecting immune cells.
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SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and less body weight gain, even after being fed a high-calorie diet.
Scientists at the Gladstone Institutes scored a rare two-for-one gain by discovering an enzyme that controls the levels of a protein implicated in both Alzheimer’s disease and frontotemporal dementia.
SAN FRANCISCO, CA—New details learned about a key cellular protein could lead to treatments for neurodegenerative diseases, such as Parkinson’s, Huntington’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS).
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure.
SAN FRANCISCO, CA—A new biopharmaceutical company, Tenaya Therapeutics Inc., will build on discoveries in cardiovascular disease research made at the Gladstone Institutes, concentrating on regenerative medicine and drug discovery fo
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes discovered that the vaginal immune system is suppressed in response to RNA viruses, such as Zika.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified two chemicals that improve their ability to transform scar tissue in a heart into healthy, beating heart muscle. The new discovery advances efforts to find new and effective treatments for heart failure.
SAN FRANCISCO, CA—Researchers at the Gladstone Institutes and UC San Francisco (UCSF) have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
SAN FRANCISCO, CA—How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation.