SAN FRANCISCO, CA—Scientists at the Gladstone Institutes discovered that an enzyme called SMYD2 could be a new therapeutic target for flushing out the HIV that hides in infected individuals. Overcoming this latent virus remains the most significant obstacle to a cure.
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SAN FRANCISCO, CA—Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit signals in the spinal cord to help control movement.
SAN FRANCISCO, CA—Scientists from the Gladstone Institutes identified that mutations in a protein commonly linked to frontotemporal dementia (FTD) result in obsessive-like behaviors.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), together with collaborators in Europe, discovered that a common type of cell within the human reproductive and intestinal tracts assists HIV in infecting immune cells.
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and less body weight gain, even after being fed a high-calorie diet.
Scientists at the Gladstone Institutes scored a rare two-for-one gain by discovering an enzyme that controls the levels of a protein implicated in both Alzheimer’s disease and frontotemporal dementia.
SAN FRANCISCO, CA—New details learned about a key cellular protein could lead to treatments for neurodegenerative diseases, such as Parkinson’s, Huntington’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS).
SAN FRANCISCO, CA—Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure.
SAN FRANCISCO, CA—A new biopharmaceutical company, Tenaya Therapeutics Inc., will build on discoveries in cardiovascular disease research made at the Gladstone Institutes, concentrating on regenerative medicine and drug discovery fo