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Recent Advances

January 17, 2017

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and less body weight gain, even after being fed a high-calorie diet.

December 15, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes linked a single gene mutation to two types of heart disease: one causes a hole in the heart of infants, and the other causes heart failure.

December 6, 2016

SAN FRANCISCO, CA—A new biopharmaceutical company, Tenaya Therapeutics Inc., will build on discoveries in cardiovascular disease research made at the Gladstone Institutes, concentrating on regenerative medicine and drug discovery fo

November 10, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes identified two chemicals that improve their ability to transform scar tissue in a heart into healthy, beating heart muscle. The new discovery advances efforts to find new and effective treatments for heart failure.

October 21, 2016

SAN FRANCISCO, CA—How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation. 

September 25, 2016

SAN FRANCISCO, CA—Stem cell experts will discuss the future of cellular reprogramming and its therapeutic potential at the Cell Symposium “10 Years of iPSCs,” September 25–27, 2016 at the Claremont Hotel and Spa in Berkeley, Califo

August 4, 2016

SAN FRANCISCO, CA—With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection.

April 28, 2016

SAN FRANCISCO, CA—In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.

March 10, 2016

SAN FRANCISCO, CA—Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation of the CRISPR-Cas9 system.

February 11, 2016

SAN FRANCISCO, CA—Scientists at the Gladstone Institutes have discovered that three transcription factors—proteins that direct gene expression—interact with each other and the genome to influence how a heart forms in an embryo.

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